Workshop on Bench to Clinic Translation in Systemic Amyloidoses

InterContinental Athenaeum Athens
September 25-26, 2023

Host: Efstathios Kastritis, MD

Organizing Committee: Efstathios Kastritis, Shaji Kumar, Giovanni Palladini, Eloisa Riva, Eli Muchtar and Stefan Schönland on behalf of ISA’s Board of Directors

ISA Sponsors:

Program Overview

Sunday September 24
7-8:30 PM: Welcome Reception (with heavy hors d’oeuvres)
Location: TOBAR (Ground Level)
Monday September 25
Location: Aphrodite I-II (Ground Level)
9:00 Welcome and Introduction: Stefan Schönland and Efstathios Kastritis
Presenter: Stefan Schönland
Introduction
Presenter: Stathis Kastritis
          Overview of Amyloid Activities in the Athens Center
9:15 Successes in Translation
Co-Chairs: Suzanne Lentzsch and Shaji Kumar
     Presenters: Per Westermark and Giampaolo Merlini
Successes in Translation
     Presenter: Shaji Kumar
Successes in Translation Survey Results
10:00 What Basic Scientists Want To Know From Clinicians
Co-Chairs: Arnaud Jaccard and Simon Gibbs
Presenters: Johannes Buchner and Stefano Ricagno
What Basic Scientists Want to Know From Clinicians
10:50 Break (Refreshments located inside Aphrodite I-II)
11:10 What Clinicians Want To Know From Basic Scientists
Co-Chairs: Marcus Faendrich and Frederic Rousseau
Presenters: Paolo Milani and Ashutosh Wechalekar
          What Clinicians Want To Know From Basic Scientists
12:00 Summary and Afternoon Agenda Preview
12:15 Buffet Luncheon (Cafezoe, Ground Level)
1:30 AL Amyloidosis- Session Introduction
Co-Chairs: Angela Dispenzieri, Alexander Carpinteiro, Thanh Huyen Phan and Joseph Jackson
     Presenters: Mario Nuvolone and Tatiana Prokaeva
Amyloidogenic LC Sequences
     Presenters: Surendra Dasari and Moshe Gatt
          Amyloidogenic Light Chains in the Blood
Presenter: Stefano Ricagno
      Discussants: Marcus Fändrich, Stefano Ricagno, Johannes Buchner, and Luis del Pozo-Yauner
Fibril in Tissue and Structure and Their Role in Pathogenesis
     Presenters: Surendra Dasari, Oshrat Rokah, and Naya Nikoalou
Organ Damage/ Tissue and Immune Microenvironment
Presenter: Christophe Sirac
          Models
4:30 Treatment of AL Amyloidosis
     Presenter: Moshe Gatt
Discussants: Suzanne Lentzsch, Vaishali Sanchorawala, Moshe Gatt and Ashutosh Wechalekar
Therapy Approaches
5:00 Summary and Tuesday Agenda Overview
S. Schönland
5:15 Session Adjourns
6:00 Reception (Premiere Rooftop Restaurant & Lounge, 10th Floor)
7:00 Dinner (Premiere Rooftop Restaurant & Lounge, 10th Floor)
Tuesday September 26
Location: Aphrodite I-II (Ground Level)

9:00 ATTR Amyloidosis–Session Introduction
Co-Chairs: Violaine Plante-Bordeneuve, Darae Kim, Paolo Milani, Kwaku Appiah-Kubi and Alberto Aimo
Presenter: Darae Kim
Treatments in ATTR Cardiomyopathy
     Presenter: Violaine Planté-Bordeneuve
Treatments in ATTR Polyneuropathy
10:00 Break (Refreshments located inside Aphrodite I-II)
10:30 ATTR Amyloidosis Discussion

12:30 Buffet Luncheon (Cafezoe, Ground Level)
1:30 Other Systemic Amyloidoses
     Co-Chairs: Bessy Ikonomidou and Chandrika Mittal
Presenter: Frederic Rousseau
          What Can We Learn From Amyloid Structures?
     Presenter: Gunilla Westermark
          IAPP, Diabetes and Putative Treatments
2:30 Break (Refreshments located inside Aphrodite I-II)
3:00 Summary and Conclusion, Including Emerging Topics
     Co-Chairs: Stefan Schönland, Stathis Kastritis, Alexander Carpinteiro, and Paolo Milani
4:45 Farewell
     Stefan Schönland, Stathis Kastritis
5:00 Workshop Adjourns
Workshop Attire

Business casual attire is suggested for the workshop but is not mandatory. Please note that the historical high temperature in September in Athens is 29C (84F), with a cooling trend late in the month. You may want to dress in layers because of the air conditioning in the hotel and meeting room.

Mask Suggestion

At this time, mask wearing during the workshop is optional.